Reduction in the Incidence of Clostridioides difficile Infection in the Intensive Care Unit of a Tertiary Care Hospital through Targeted Infection Prevention and Control Strategies
Tanu Singhal, Sweta Shah, Ganesh Madhu, Reshma Tejam, Remya VadiyarAbstract
Context:
Aims:
This study aimed to report changes in the incidence rate of CDI and review infection prevention and control strategies.
Settings and Design:
This retrospective study was conducted between 2018 and 2024 in a tertiary care hospital in Mumbai, India.
Subjects and Methods:
Patients with suspected CDI were first tested with by polymerase chain reaction; if positive, then for CDAB toxin.
Statistical Analysis Used:
Data was summarized as percentages and incidence rates per 1000 patient days.
Results:
A total of 135 patients developed CDI, with an average incidence of 0.6/1000 patient days. The crude mortality rate was 16%.
Conclusions:
Addressing the key gaps of inadequate cleaning, incorrect disinfectant dilution, and improper duster usage helped achieving reduction in the incidence of CDI.