DOI: 10.1001/jamadermatol.2026.2075 ISSN: 2168-6068

Recurrent Giant Tendinous Masses and Refractory Hypercholesterolemia in a Woman

Yu Fan, Yuanyuan Li, Yiwen Wu

A woman in her 30s presented with a 22-year history of progressively enlarging, painless subcutaneous nodules that first appeared on her Achilles tendons during adolescence and eventually involved the elbows, wrists, knees, and iliac crests. What is your diagnosis?

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