Recent Innovations in Carbohydrate Synthesis
Authors not availableNew Strategies for Building Complex Carbohydrates with Precision. Carbohydrates are among the most biologically important molecules in nature, yet constructing them with precise stereochemistry remains a formidable challenge. Multiple stereogenic centers, reactive hydroxyl groups, and the complexity of glycosidic bond formation have driven continuous innovation in this field. This volume surveys topics across synthetic carbohydrate chemistry, from data-driven approaches that predict stereochemical outcomes to visible-light and photoredox methods that enable transformations once considered inaccessible. Chapters span the full landscape of modern glycosidic bond formation, including O-, C-, and S-glycosylation, transition-metal-catalyzed cross-coupling, glycal-based strategies, and green synthetic methods, while also addressing applications in drug discovery and human health. This work will appeal to organic chemists, carbohydrate chemists, medicinal chemists, and drug discovery researchers seeking current perspectives on the latest synthetic strategies.