DOI: 10.1002/efd2.70023 ISSN: 2666-3066
Recent advances on the impact of protumorigenic dietary‐derived bacterial metabolites on the intestinal stem cell
Carys Holmes, Charlotte H. Illingworth, Lee ParryAbstract
The links between diet, microbiome, immunity, and colorectal cancer are well established. The metabolite output of the microbiome, which has a large influence over host health and disease, is related to the composition of the diet. These metabolites subsequently impact on immune and intestinal epithelial either directly or indirectly via production of secondary metabolites. Here we summarize the latest findings and briefly discuss their potential for managing disease risk.