Real‐World Perioperative and Early Oncological Outcomes of Robot‐Assisted Nephroureterectomy for Upper Tract Urothelial Carcinoma: A Single‐Institution Series of 100 Consecutive Patients

ABSTRACT

Robot‐assisted radical nephroureterectomy (RANU) is increasingly used for upper tract urothelial carcinoma (UTUC), yet most published series are selected and real‐world data from consecutive, unselected practice are scarce. We reviewed 100 consecutive RANU performed at a single institution between April 2022 and March 2026, including six cases with a concomitant procedure. Median age was 77 years and 39 patients had pT3–4 disease. Median estimated blood loss was 29 mL, operative time 200 min, and console time 141 min; three patients required transfusion. Clavien–Dindo grade II or higher complications occurred within 90 days in 13 patients, with only one grade III event. At a median follow‐up of 15.5 months, the cumulative incidence of intravesical and of distant or local recurrence was approximately 17% and 18% at 12 months, and overall survival was approximately 86% at 24 months. RANU was feasible with favorable perioperative outcomes in this elderly, frequently advanced cohort.