DOI: 10.1039/d6ra04159k ISSN: 2046-2069
Quantum dot (QD)-based silicon as an efficient catalyst for the one-pot synthesis of polynuclear acridines: molecular docking investigation of putative anti-tubercular and anti-HIV drug candidates
Mahmoud Tarek, Gehad E. Said, Mohamed A. Al-Omar, Abdulrahman A. Almehizia, Ahmed M. Naglah, Alia Alshammari, Hazem A. Ghabbour, Tamer K. KhatabSilicon quantum dots (Si-QDs) were utilized as a nano-catalyst in the one-pot synthesis of some new 1,8-dioxodecahydroacridine frameworks. The synthesized acridine derivatives undergo docking validation as anti-tubercular and anti-HIV agents.