Quality of Life in Children with Celiac Disease: The Turkish Version of the Celiac Disease Dutch Questionnaire Scale
NEO Sukur, BO Bakır, İK CebioğluContext:
Celiac disease (CD), affecting approximately 1% of people worldwide, often reduces health-related quality of life (HRQoL) due to pre-diagnosis gastrointestinal symptoms. Although strict adherence to a gluten-free diet (GFD) relieves symptoms, it imposes social limitations that further reduce HRQoL. Assessing HRQoL, a key patient-reported outcome, is essential in both research and clinical practice.
Aims:
The study aimed to validate and assess the reliability of the Turkish Celiac Disease Dutch Questionnaire (CDDUX).
Settings and Design:
Methodological, cross-sectional study following STROBE guidelines.
Methods and Materials:
Based on the ten-times rule, a minimum sample of 120 required; with 10% attrition, 132 dyads were targeted. Children aged 8–18 years with CD and their parents from celiac associations participated voluntarily. Ethical approval and informed consent were obtained. Data were collected using the CDDUX, pediatric quality of life inventory (PedsQL), and a socio-demographic questionnaire.
Statistical Analysis Used:
Data were analyzed using Statistical Package for Social Sciences (SPSS version 25, IBM, Illinois, California) for Windows.
Results:
The CDDUX-children (CDDUX-C) and CDDUX-parents (CDDUX-P) demonstrated high reliability. CDDUX and PedsQL scores were weakly but significantly correlated in both children and parent results. CDDUX-C total scores were significantly higher than CDDUX-P, and children of single parents reported higher HRQoL than those of married parents for both CDDUX-C and CDDUX-P.
Conclusions:
The Turkish version of the CDDUX scale is a valid and reliable tool for assessing the HRQoL of children with CD. Evaluating the independent variables that influence children’s HRQoL can help researchers develop effective interventions.