Q-switched Ruby Laser (694 nm) for the Treatment of Axillary Hyperpigmentation among Adult Female Patients with Skin Phototype III–IV: A Single-blind Randomized Controlled Trial
Ana Rouselle Arcilla Reyes-Ramos, Roberto Antonio Borromeo Pascual, Lian Cruz JamisolaAbstract
Background:
Axillary hyperpigmentation is a prevalent cosmetic concern among individuals with darker skin tones, particularly among women with Fitzpatrick skin types III–VI. Despite the widespread use of topical depigmenting agents, their efficacy remains inconsistent, necessitating the exploration of alternative treatment modalities. Q-switched Ruby Laser (QSRL, 694 nm) has been widely used for pigmentary disorders but not extensively for axillary hyperpigmentation.
Objective:
The objective of the study was to assess the efficacy, safety, and patient satisfaction of QSRL treatment in reducing axillary hyperpigmentation.
Materials and Methods:
This is a single-center, single-blinded, randomized-controlled trial. Twenty female participants (aged 19–60 years) with bilateral axillary hyperpigmentation were enrolled. Each axilla was randomly assigned to treatment and control group. The QSRL was administered to treatment group, in five sessions with 2-week follow-up. Outcomes included melanin index reduction, decrease on Von Luschan Chromatic Scale (VLCS), erythema, patient-reported pain, and treatment satisfaction. Statistical analyses were done.
Results:
Treatment group showed a significant decrease in melanin index (
Conclusion:
QSRL is a safe, effective, and well-tolerated treatment for axillary hyperpigmentation in women with skin types III–IV. Significant improvement in melanin index, skin tone reduction, and high treatment satisfaction rates highlight its potential as an alternative to topical depigmenting agents.