DOI: 10.1039/d6tb01072e ISSN: 2050-750X

Pulmonary behaviour of ultrasmall CeO 2 nanoparticles: rapid cerium reduction and phosphate immobilisation in vivo

Tatiana V. Plakhova, Anna Yu. Romanchuk, Sofia Yu. Khabirova, Tatiana O. Abakumova, Gleb Yu. Aleshin, Anna V. Ivanova, Maxim A. Abakumov, Adrian V. Zavodov, Andrey A. Shiryaev, Alexander L. Trigub, Stepan N. Kalmykov
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CeO 2 nanoparticles undergo redox transformation in the lungs, forming needle-like Ce(

iii
) phosphate crystallites enriched with calcium and potassium. These changes may contribute to the prolonged retention of cerium in lung tissue.

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