DOI: 10.4103/ojo.ojo_481_25 ISSN: 0974-620X

Pseudoexfoliation syndrome in Omani patients undergoing cataract surgery

Hajar AlAamri, Haitham Al Mahrouqi

Abstract:

BACKGROUND:

Pseudoexfoliation (PXF) syndrome is an age-related ocular condition characterized by the deposition of typical PXF material on the anterior lens capsule and other anterior segment structures. PXF is associated with cataract, glaucoma, lens instability, and an increased risk of complications during cataract surgery.

OBJECTIVE:

This study aimed to assess the prevalence and clinical characteristics of PXF among Omani patients undergoing cataract surgery at Al Nahda Hospital and to describe associated ocular conditions and surgical complications.

METHODS:

A retrospective cross-sectional study was conducted among Omani patients aged 40 years or older who underwent cataract surgery between January 1, 2023, and June 30, 2023. Demographic, preoperative, intraoperative, and postoperative clinical data were collected and analyzed.

RESULTS:

A total of 600 eyes from 578 patients were included. PXF was diagnosed in 70 patients (71 eyes), corresponding to a patient-level prevalence of 12.1% (70/578; 95% confidence interval, 9.56%–15.05%). PXF was present in 49 of 332 female patients (14.8%) and 21 of 246 male patients (8.5%), with a statistically significant association between sex and PXF (Pearson χ 2 = 5.140, P = 0.023). Patients with PXF were significantly older than those without PXF (71.29 ± 6.67 vs. 64.54 ± 10.75 years; P < 0.001). Among the 71 PXF eyes, nuclear sclerotic cataract was present in 100%, and glaucoma was present in 45.1%. Intraoperative complications included iris trauma in 6 eyes (8.5%), posterior capsular tear in 4 eyes (5.6%), and dropped nucleus in 4 eyes (5.6%); anterior vitrectomy was performed in 4 eyes (5.6%).

CONCLUSIONS:

PXF was present in 12.1% of Omani patients undergoing cataract surgery in this study and was associated with older age and a high prevalence of glaucoma. Recognition of PXF before cataract surgery and appropriate surgical precautions may help reduce the risk of intraoperative complications.

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