PS63 Systematic review to identify existing patient-reported outcome measures capturing appearance-related concerns for utilization in acne

Abstract

Acne is an inflammatory dermatological condition that causes significant psychosocial impact. There is no universally recognized patient-reported outcome measure (PROM) for use in both clinical and trial settings that captures the impacts of acne most important to patients. Appearance-related concerns is one of six domains identified by the Acne Core Research Outcomes Network as a theme of central importance to patients. Further work has subcategorized this into three subdomains of negative self-­perception: self-image, self-concept, and self-consciousness/self-conscious emotions. Future PROMs for use in acne need to capture all three subdomains. We aimed to identify body image PROMs capturing all three subdomains of negative self-­perception within appearance-related concerns and determine their validation for use in acne. Publications relating to body image and appearance were identified using search criteria utilized by a previous systematic review of body image scales. PROMs used in the identified publications were extracted. Those meeting a pre­defined description of body image were analysed to see whether they captured all three subdomains of negative self-perception and relevance to acne. A further search checked whether any were validated for use in acne. In total, 333 PROMs were extracted; 100 met the definition of body image and 22 PROMs captured all three subdomains of negative self-perception. Five PROMs contained items relevant to acne, including the Derriford Appearance Scale, Body and Appearance Self-conscious Emotions Scale, Body Image Concerns Inventory, Body Image Coping Strategy Inventory, and Body Image Psychological Inflexibility Scale. The literature search did not identify publications validating these PROMs for use in acne. Further work is required with the support of people with acne to review the five PROMs containing questions relevant to acne and, if appropriate, to validate them for use in acne. If they are not appropriate the development of a new PROM capturing appearance concerns in acne is needed.