Protective role of dietary antioxidant intake on long-term effects of extreme PM2.5 exposure on respiratory health
Thara Govindaraju, Catherine L Smith, Jillian Ikin, Alice J Owen, Matthew Carroll, Brigitte M. Borg, Caroline X Gao, David Brown, David Poland, Shantelle Allgood, Michael J Abramson, Karen Walker-Bone, Tracy A McCaffrey, Tyler J LaneObjective:
To test whether dietary antioxidants moderated effects of PM 2.5 from coal mine fire smoke on respiratory symptoms.
Methods:
We conducted cross-sectional analyses of diet and respiratory symptom data from 448 members of the Hazelwood Health Study Adult cohort. Individual-level exposure to PM 2.5 from the 2014 coal mine fire was determined by combining modelled fire-related PM 2.5 estimates and time-location diaries from the time of the fire. Data were evaluated using logistic regressions to evaluate associations between PM 2.5 and respiratory symptoms and whether this was moderated by meeting recommended daily antioxidant intakes.
Results:
Vitamins A and E, magnesium, and zinc attenuated the association between PM 2.5 and chronic cough and (excluding magnesium) chronic phlegm. Omega-3 fatty acids attenuated the association between PM 2.5 and COPD.
Conclusion:
Higher-quality diets may reduce harms due to smoke exposure from landscape fires.