DOI: 10.1097/inf.0000000000005456 ISSN: 0891-3668
Proportion of Colonized Person-time With Streptococcus pneumoniae and Duration of Colonization With Individual Serotypes in Young Peruvian Children
Leigh M. Howard, Xiang Huang, Kathryn M. Edwards, Yuwei Zhu, Marie R. Griffin, Jorge E. Vidal, Keith P. Klugman, Ana I. Gil, Nicole R. Soper, Isaac P. Thomsen, Katherine Gould, Jason Hinds, Claudio F. Lanata, Carlos G. GrijalvaFew studies have characterized the proportion of time a child spends with nasopharyngeal pneumococcal colonization, thus at risk for pneumococcal disease. In this prospective study conducted in the early 7-valent pneumococcal conjugate vaccine implementation period, young Peruvian children exhibited pneumococcal colonization during half of the observed person-time. Specific serotypes exhibited variable colonization duration, ranging from 17.5 to 100.3 days.