Programmable RNA therapeutics: from intracellular sensing to cell-specific delivery

“...one major sign of success would be havingmultiple clinically validated platforms that can reproducibly deliver different RNA cargoes...”Jokūbas Leikauskas, Editor, Nucleic Acid Insights, speaks to Charannya Sozheesvari Subhramanyam, Scientist, A*STAR Institute of Molecular and Cell Biology, about the current challenges and emerging strategies in achieving tissue- and cell-specific delivery of RNA therapeutics, exploring how programmable RNA sensing technologies could unlock the next level of precision in targeted RNA medicine.