DOI: 10.17116/anaesthesiology202501136 ISSN: 0201-7563

Prognostic capabilities of the sofa score in patients with thermal injury

E.A. Zhirkova, T.G. Spiridonova, A.V. Sachkov, E.I. Eliseenkova, I.G. Borisov, A.O. Medvedev, M.L. Rogal, S.S. Petrikov

The SOFA scale should be used to predict the outcomes of thermal injury. Objective. To study the possibilities of the SOFA scale in predicting the outcomes of thermal injury in stratification groups of revised Frank index (RFI). Material and methods. A retrospective study included 196 patients stratified into 3 groups: RFI≤70 (54 patients, all survived), RFI 71—180 (120 patients: 96 survived, 24 died), RFI≥181 (22 patients, all died). We analyzed SOFA scores within 3 days after injury (SOFA1, SOFA2, SOFA3) and compared in patients of three groups stratified by RFI including between patients with RFI≤70 and survivors with RFI 71—180, survivors and deceased patients with RFI 71—180, with RFI ≥181 and deceased patients with RFI 71—180. Results. SOFA score within 3 days after injury was significantly higher in deceased patients compared to survivors. After 3 days, SOFA scores were similar (in patients with RFI≤70 and survivors with RFI 71—180, as well as in patients with RFI≥181 and deceased patients with RFI 71—180). Scores were significantly higher in deceased patients with RFI 71—180 compared to survivors for 3 days. ROC analysis of injury outcome depending on SOFA1, SOFA2 and SOFA3 scores showed that all areas under ROC curves (AUCs) exceeded 0.9 with maximum AUC for SOFA3 (0.960). The cutoff point for SOFA1-SOFA3 was SOFA score ≥4. SOFA score ≥4 predicted unfavorable outcomes, SOFA score<4 predicted favorable outcomes. Conclusion. SOFA score characterized clinical severity in RFI-stratified groups. SOFA score ≥4 predicted unfavorable outcomes. Prediction of outcomes after thermal injury using SOFA scale is the most relevant for patients with RFI 71—180.

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