Outline
DOI: 10.1039/d4cb00053f ISSN: 2633-0679
Probing the metalloproteome: an 8-mercaptoquinoline motif enriches minichromosome maintenance complex components as significant metalloprotein targets in live cells
Sean M. McKenna, Bogdan I. Florea, Daniela M. Zisterer, Sander I. van Kasteren, Joanna F. McGouranA mercaptoquinoline based photo affinity probe for profiling metalloproteins was developed and applied in live cell assays, identifying several novel, therapeutically significant protein targets.
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