Outline
DOI: 10.1039/d6dt01270a ISSN: 1477-9226
Probing the drug–DNA interactions of new cytotoxic fluorinated platinum(
ii
) complexes
Giulia Coffetti, Conor Newsome, Eoin Walsh, Michael S. Christodoulou, Luisa Doneda, Francesca Paino, Augusto Pessina, Giorgio Facchetti, Emilio Ciusani, Andrew Kellett, Isabella Rimoldi A new series of fluorinated 8-aminoquinoline and 8-aminoquinaldine platinum dichloride complexes (1–5) is presented in this work, examining their anticancer potential and interactions with DNA under in vitro conditions.
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