DOI: 10.1002/slct.74994 ISSN: 2365-6549

Probing Inclusion Complexation of a Biologically Potent Molecule With α‐Cyclodextrins by Crystal Diffraction Studies

Antara Sharma, Pranish Bomzan, Ashis Chhetri, Debadrita Roy, Mahendra Nath Roy

ABSTRACT

The crystal structure of the 1:1 inclusion complex of α‐cyclodextrin (with Rhodanine) was established by x‐ray diffraction. This complex crystallizes in hexagonal crystal system with the space group P6, characterized by a head‐to‐tail channel‐type packing arrangement. Co‐crystallized water molecules are also partially present in eight lattice point. The guest molecule Rhodanine is placed inside the α‐cyclodextrin cavity.

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