Primary Gestational Choriocarcinoma of the Cervix in an Ectopic Cervical Pregnancy: Diagnosis and Treatment—A Case Report and Review of the Literature
Dimitrios Panagiotopoulos, Evangelos Vafias, Konstantinos Chatzidimitriadis, Ioannis Georgios Zacharias, Paraskevi Alexandrou, Elena Alchazidou, Ioanna Petrakou, Georgios PetrakosBackground/Objectives: Gestational choriocarcinoma is an uncommon neoplasia related to pregnancy. Signs and symptoms remain unspecific, while abnormal uterine bleeding is the main symptom. Methods: We report a case of a 40-year-old woman with gestational choriocarcinoma presenting as cervical ectopic pregnancy and a review of the literature. Results: After emergency evaluation, acute blood loss was controlled surgically. Diagnosis was set by histological examination of the uterus. Histological confirmation typically is difficult, due to high vascularization of the lesions. Conclusions: Diagnosis requires a high level of clinical suspicion, correlation with laboratory findings and specialized histopathological confirmation in cases which biopsy is offered. Treatment with chemotherapy is the main way of management, achieving treatment and fertility preservation. Surgical intervention is required for cases complicated by hemorrhage leading to hemodynamic instability.