Prevalence of dyslipidaemia in patients diagnosed with de novo adhesive capsulitis: A cross-sectional study
ADINARAYANA KASHYAP TADIKONDA, DEEPAK KUMAR MALEY, SREEDHAR SATHU, SYED IFTHEKAR, DEEPANKAR SATAPATHY, RAVI KUMAR, SRIKANTH EPPAKAYALA, CHRISTINA BODA, MAHESHWAR LAKKIREDDYBackground
Adhesive capsulitis is an idiopathic condition characterized by painful restriction of shoulder movements, with diabetes mellitus identified as a commonly associated factor. Dyslipidaemia has been suggested as a potential contributing factor. Additionally, elevated inflammatory lipoprotein levels, particularly hyper-low-density lipoproteinaemia and hyper-non-high-density lipoproteinaemia, along with increased glycosylated haemoglobin (HbA1c) levels, might contribute to the inflammatory process and stiffness observed in adhesive capsulitis. We aimed to determine the prevalence of dyslipidaemia in patients diagnosed with de novo adhesive capsulitis and assess the correlation of various parameters measured in subjects with adhesive capsulitis.
Methods
This cross-sectional study was conducted in the orthopaedics department of a tertiary care medical centre, assessing patients clinically diagnosed with adhesive capsulitis between April and December 2023. Biochemical analyses, including fasting lipid profiles, were conducted. Patients with known diabetes or pre-existing shoulder pathologies were excluded.
Results
Seventy-three subjects diagnosed with adhesive capsulitis were included, with a mean age of 52.3 (7.8) years. Among them, 40 (54.8%) were females, and 33 (45.2%) were male. Elevated levels of total cholesterol were observed in 46 (63%) patients, triglycerides in 36 (49.3%), low-density lipoprotein in 35 (47.9%), and very low-density lipoprotein in 44 (60.3%). Elevated fasting blood sugars were found in 14 (19.2%) patients, post-prandial in 17 (23.8%), and HbA1c in 31 (42.4%).
Conclusion
Inflammatory lipoproteinaemia, particularly hyper-low-density lipoproteinaemia, hyper-non-high-density lipoproteinaemia, and elevated HbA1c levels, were prevalent among patients newly diagnosed with adhesive capsulitis.