Prevalence and Incidence of Dementia for Schizophrenia and Other Primary Psychotic Disorders: A Systematic Review and Meta‐Analysis
Mengyi Gao, Minxiu Ji, Caidi Zhang, Shuying Wang, Chun Wang, Yikang Zhu, Xiaochun Qiu, Raymond C. K. Chan, Stefan Leucht, Xinyi Cao, Chunbo LiABSTRACT
People with psychotic disorders have higher dementia risk. This study aimed to investigate the prevalence and incidence of dementia in this population. Data were synthesized through meta‐analysis (including subgroup and sensitivity analyses) and narrative synthesis. The pooled dementia prevalence was 24.3% (95% CI: 20.5%–28.5%, I 2 = 84.7%, p < 0.001) in older adults after excluding one outlier. Factors contributing to heterogeneity included prevalence types, settings, geographical regions, and age. The dementia incidence varied widely. This review identified elevated but heterogeneous dementia rates in psychotic disorders, calling for more population‐based studies to provide evidence for integrated service planning.