DOI: 10.4103/jdras.jdras_349_24 ISSN: 2279-0357
Preparation and preliminary analysis of Gandharvahastadi Eranda Taila
P. M. Adarsh, Anup B. Thakar, C. R. Harisha Abstract
BACKGROUND:
Virechana
(therapeutic purgation) is one of the premier
Panchakarma
procedures, which utilizes a variety of medicinal formulations based on the patient’s condition and disease.
Gandharvahastadi Eranda Taila
(GT) is a modified Ayurvedic herbal formulation used for the purpose of both
shamana
(pacifying therapy) and
shodhana
(purifying therapy). Drug standardization is the first step in drug quality assurance. The present study aims to prepare and develop the quality standards for GT.
METHODS:
All the ingredients of GT were procured from the pharmacy of the Institute of Teaching and Research in Ayurveda (ITRA), Jamnagar, except
Musali
and
Chirabilva
, which were procured from Herbs India Pharma, Ernakulam, Kerala.
Chitraka
was purchased from the local market of Jamnagar. The ingredients were powdered separately and subjected to pharmacognostic evaluation at the pharmacognosy laboratory of ITRA, Jamnagar, and cross-verified against the Ayurvedic Pharmacopeia of India (API). GT was prepared in the ITRA pharmacy following the general method for preparing medicated oil in the Ayurvedic Formulary of India. Pharmaceutical analysis of GT was performed in the pharmaceutical laboratory at ITRA in accordance with the guidelines for physical tests of APIs. Microbiological studies were conducted in the ITRA microbiological laboratory at regular intervals over a 1-year period.
RESULTS:
The specific gravity of the product was standardized as 0.960 ± 0.043. The acid value was calculated as 3.93 ± 0.065. Saponification value, iodine value, and peroxide value were recorded as 195.15 ± 6.50, 119.5 ± 5.8, and 3.17 ± 0.01, respectively. There were no microbial or fungal contaminants in the study sample till the last turn of the microbiological study.
CONCLUSION:
The pharmaceutical evaluation of GT and the pharmacognostic evaluation of the individual ingredients in GT established preliminary standards for the quality control of GT, whereas the microbiological study indicates GT’s stability and better shelf life.