DOI: 10.1093/cid/ciae626 ISSN: 1058-4838

Population-Based Analysis of the Risk of Mycobacterial Infections Associated With Immune Checkpoint Inhibitors

Marie Yan, Alejandro Hernandez, Kelvin K Chan, Matthew B Stanbrook, Phillip S Blanchette, James C Johnston, Samantha M Lee, Liane Macdonald, Melissa Richard-Greenblatt, Theodore K Marras, Sarah K Brode

Abstract

In this population-based study, we examined the risk of nontuberculous mycobacterial disease associated with immune checkpoint inhibitors among people with cancer. Using a nested case-control design, we identified 184 cases and 714 matched controls; there was no significant association on conditional logistic regression (adjusted odds ratio, 0.51 [95% confidence interval, .17–1.50]; P = .22).

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