DOI: 10.1001/jama.2026.17268 ISSN: 0098-7484
Polypharmacy and Drug-Drug Interactions Among Older Adults
Dima Mazen Qato, Jocelyn Wilder, Shyam Krishnan Ondanat Veetil, Qingrong (Jessica) Li, Rupshikha Sen, G. Caleb AlexanderThis study uses a nationally representative sample to estimate changes in the use and concurrent use of prescription and over-the-counter (OTC) medications and dietary supplements among older adults in the US between 2015-2016 and 2021-2023, including use of potentially major drug-drug interactions.