DOI: 10.1039/d6pm00029k ISSN: 2976-8713

PLGA and Eudragit-based long-acting microspheres for Parkinson's disease management

Deepa D. Nakmode, Haripriya Koppisetti, Weranga Rajapaksha, Yunmei Song, Sanjay Garg

A long-acting PLGA/Eudragit microsphere formulation was developed to replace frequent oral dosing for Parkinson's disease. It successfully delivered hydrophilic pramipexole, achieving sustained release for up to 18 days with excellent syringeability.

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