DOI: 10.1093/eurpub/ckag169.684 ISSN: 1464-360X

Plant-Based Dietary Patterns, ultra-processed foods and NCD Prevention

AM Pezzullo, L Villani, M Bonaccio

Abstract

Plant-based dietary patterns encompass a spectrum ranging from vegan and vegetarian diets, which exclude some or all animal-source foods, to more flexible approaches such as pescatarian and flexitarian diets, as well as whole-food plant-based patterns emphasizing minimally processed foods. In public health epidemiology, these distinctions are functionally relevant because health outcomes depend not only on the proportion of plant foods consumed but also on overall dietary quality and degree of food processing. Diets rich in vegetables, fruits, whole grains, legumes, nuts, and seeds are consistently associated with reduced risk of major non-communicable diseases (NCDs), including cardiovascular disease, type 2 diabetes, and certain cancers. However, growing consumption of ultra-processed foods (UPFs), as defined by the NOVA classification, has introduced new challenges within plant-based dietary transitions. Industrial plant-based products, such as meat and dairy alternatives, differ substantially from minimally processed plant foods in nutritional composition and food matrix. Epidemiological evidence consistently associates high UPF intake with increased risk of NCDs, including cardiovascular disease and type 2 diabetes. These findings suggest that plant-based UPFs may not provide the same health benefits as whole-food plant-based diets, despite their plant origin. The “health halo” associated with plant-based labeling may lead consumers to overestimate the nutritional value of highly processed products, highlighting limitations of regulatory frameworks that emphasize nutrient composition while overlooking food processing. Overall, current evidence indicates that the health and sustainability benefits of plant-based diets depend not simply on replacing animal foods with plant-derived alternatives, but on prioritizing minimally processed, nutritionally balanced dietary patterns.

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