Phytochemicals and anti-aging antioxidant potential of Julang jaling (Archidendron bubalinum (Jack) I.C. Nielsen) extract

Numerous variables, notably reactive oxygen species (ROS), have an impact on aging. When not counterbalanced by antioxidants, excessive ROS results in oxidative stress, which causes wrinkles, black spots, and diminished skin flexibility. Natural sources are seen as safe and effective antioxidants that aid in cell protection against ROS damage. One promising candidate antioxidant and anti-aging is Archidendron bubalinum extract (ABE) from the plant Julang-Jaling (Archidendron bubalinum (Jack) I.C.Nielsen ). The capability of ABE to counteract free radicals and lessen oxidative stress was measured using two methods: (2,2-diphenyl-1-picrylhydrazyl) (DPPH) and (2,2'-azinobis(3-ethylbenzothiazoline-6-sulfonic acid)) ABTS radical scavenging assays. Meanwhile, the potential for anti-aging was evaluated by looking at how well ABE inhibits elastase and collagenase activity since these enzymes play a key role in breaking down structural proteins in the skin. Phytochemical screening revealed that ABE contains high levels of alkaloids and saponins (+++), moderate levels of flavonoids (++), and low levels of phenols and tannins (+). These bioactive compounds are consistent with the strong antioxidant activity observed, with IC50 values of 26.39 ± 0.78 µg/mL (DPPH) and 6.37 ± 0.43 µg/mL (ABTS). In addition, ABE showed significant elastase inhibition (IC50 31.98 ± 0.47 µg/mL) and moderate collagenase inhibition (IC50 127.62 ± 7.01 µg/mL), indicating its potential role in protecting skin structure and elasticity. Archidendron Bubalinum Extract (ABE) shows significant antioxidant and anti-aging properties, which supports its continued advancement for use in functional food and cosmetic products.