Persistent Colonic Activity on 99mTc-MDP Whole Bone Scintigraphy Revealing a Complex Ureterorectal Fistula

Intense bowel activity on ^99m Tc-MDP bone scintigraphy is often dismissed as urinary contamination or radiopharmaceutical instability, but persistent uptake should prompt an anatomic search. A 68-year-old woman with metastatic cervical squamous cell carcinoma after radical pelvic surgery underwent bone scintigraphy for suspected left-foot metastasis. Images showed sacral/pelvic metastases, benign-appearing calcaneal uptake, and organized colonic activity. Contrast-enhanced CT revealed a complex fistulous tract connecting the left distal ureter, vaginal stump, rectum, and sigmoid colon. Follow-up pelvic SPECT/CT localized persistent activity to the rectosigmoid lumen, confirming fistula-related intraintestinal urine. Recognition redirected interpretation from artifact to actionable urinary-enteric fistula with clinical implications.