DOI: 10.1172/jci.insight.203805 ISSN: 2379-3708
Periostin defines a pathological fibroblast program enriched in restrictive allograft syndrome
Yudai Miyashita, Taisuke Kaiho, Yuriko Yagi, Taichi Nagano, Xin Wu, Yuanqing Yan, Haiying Sun, Carl Atkinson, GR Scott Budinger, Ankit Bharat, Chitaru KuriharaThis study identifies POSTN-positive pathological fibroblasts as key contributors to fibrotic restrictive chronic lung allograft dysfunction after lung transplantation.