Perianal hidradenoma papilliferum in a male: A case report and review of the literature

Introduction: Hidradenoma papilliferum is a rare, benign, predominantly cystic tumor that predominantly affects women between 30 and 60 years of age. It is thought to originate from anogenital mammary-like glands, and therefore most commonly arises in the anogenital region. Clinically, it typically presents as a slow-growing, solitary, circumscribed nodule measuring between 0.5 cm and 2.0 cm in diameter. Case Report: We report a rare case of a perianal hidradenoma papilliferum in a 70-year-old male who presented with a 2 cm highly pedunculated perianal lesion at the anal verge. This lesion had reportedly been present for several months and had recently increased in size. A literature review was completed and a total of 15 cases of hidradenoma papilliferum were identified in men, of which only three involved the perianal region. The majority of cases (9/15) were located in the head and neck region. Conclusion: We therefore report a new case of this rare entity. To our knowledge, this is only the fourth documented case of perianal hidradenoma papilliferum in a male patient.