DOI: 10.1001/jamaophthalmol.2026.4512 ISSN: 2168-6165

Performance of Frontier Multimodal Large Language Models on Ophthalmology Cases

Shayaan Kaleem, Andrew Mihalache, Helen Peng, Umar Rahman, Ehsan Timajchi, Kobiga Seralathan, Sameen Kaleem, Marko M. Popovic, Rajeev H. Muni

This cross-sectional study compares 3 large language models on the accuracy of their responses to optical coherence tomography image–based and non–image-based questions.

More from our Archive