Performance comparison of peripheral defocus spectacle lenses

Aims/Purpose: To compare the effectiveness of myopia control spectacle lenses with Highly Aspherical Lenslets (HAL) to Defocus Incorporated Multiple Segments (DIMS) in European children with progressive myopia after 12M & 24M of lens usage.

Methods: In this retrospective study, data from 146 progressive myopic patients (73 treated with DIMS vs. 73 treated with HAL), aged 6‐17 years (mean age ±SD, 11.3±2.36) with Spherical Equivalent Refraction (SER) between ‐0.50D to ‐9.25D and no associated ocular pathology were included. Spherical equivalent refraction (SER) and axial length (AL) were measured at baseline, 12M and 24M.

Results: The mean change in SER from baseline to 12M and baseline to 24M for the HAL and DIMS groups were ‐0.30±0.30D and ‐0.34±0.46D (12M) and ‐0.63±0.56D and ‐0.50±0.64D (24M), respectively. The mean difference was ‐0.04 (95%CI: ‐0.17 ‐ 0.08) at 12M and ‐0.13 (95%CI: ‐0.07 ‐ 0.32) with no statistically significant difference between the two groups both at 12M and 24M (Mann‐Whitney U Test, p = 0.80 and p = 0.05 respectively). The mean change in AL from baseline to 12M and baseline to 24M for the HAL and DIMS groups were 0.15±0.47mm and 0.19±0.56mm (12M) and 0.32±0.72mm and 0.29±0.63mm (24M), respectively. The mean difference was 0.04 (95%CI: ‐0.13 ‐ 0.21) and ‐0.03 (95%CI: ‐0.25 ‐ 0.19) with no statistically significant difference between the two groups both at 12M and 24 M (Mann‐Whitney U Test, p = 0.34 and p = 0.71 respectively).

Conclusions: Data from these retrospective analyses demonstrate and highlight that both optical interventions are effective in controlling myopia progression at 12M and 24M (i.e. non‐inferiority of DIMS vs. HAL) in European children with progressive myopia.