Patient-reported Outcomes and Health-related Quality of Life in Lung Cancer: A Bibliometric Analysis
Totygul Hairollakyzy Nurseitova, Akmaral Muhambetzhanovna Baspakova, Azhar Nikolaevna Zhexenova, Nursaule Tangmaganbetkyzy Bagtygaliyeva
A
BSTRACT
Background:
Lung cancer remains the leading cause of cancer-related mortality worldwide. With advances in systemic therapies and improved survival, health-related quality of life (HRQoL) has become a key endpoint in oncology research. The increasing volume of literature in this field necessitates a bibliometric evaluation.
Objective:
To analyze the global scientific landscape of quality of life (QoL) and patient-reported outcomes (PROs) research in lung cancer from 2000 to 2025.
Materials and Methods:
A bibliometric analysis was conducted using the Web of Science Core Collection. Articles and reviews were identified using topic-based search terms related to lung cancer, QoL, and PROs. Data were analyzed using the bibliometrix R package and Biblioshiny. Publication trends, citation patterns, leading journals, institutions, countries, and keyword dynamics were assessed.
Results:
A total of 702 publications from 245 sources were included. Research output increased markedly after 2018, peaking around 2022. The United States and China were the leading contributors, with strong international collaboration. The most influential journals included
Conclusion:
Research on QoL in lung cancer has expanded significantly and underscores the importance of PROs in modern oncology. Integration of QoL assessment into clinical practice enables better evaluation of treatment effectiveness, early detection of toxicity, and more personalized patient management. These findings support the implementation of patient-centered approaches in routine care and health policy.