DOI: 10.1039/d4qo00560k ISSN: 2052-4129
Palladium/copper-cocatalyzed three-component tandem cyclization of o-alkenyl arylisocyanides and sulfur ylides with alcohols: direct synthesis of spiro 3,3′-cyclopropyl oxindoles
Yue Gong, Xue-Cen Xu, Zi-Xuan Yang, Yu-Long ZhaoA novel palladium/copper-cocatalyzed tandem cyclization of o-alkenyl arylisocyanides and sulfur ylides with alcohols has been developed, providing a simple and efficient method for the synthesis of spiro 3,3′-cyclopropyl oxindoles in a single step.