DOI: 10.1039/d6ob01390b ISSN: 1477-0520

Palladium-catalyzed cascade imidoylative Heck annulation of functionalized isocyanides for the construction of 1,4-diazepinones

Ling Zhong, Haixia Zhao, Sheng Wu, Ye Zhang, Yiman Zhong, Chen Chen

A palladium-catalyzed cascade imidoylative Heck annulation of functionalized isocyanides with aryl iodides provides efficient access to seven-membered 1,4-diazepinones bearing an exocyclic alkene in yields of up to 92%.

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