Paediatric Hodgkin Lymphoma Therapy: A Synthetic Update

Classic Hodgkin lymphoma in children is a malignant disease with a high cure rate. It is therefore evident that minimizing the acute and chronic toxic effects of the therapies used is a crucial issue in early ages. Radiotherapy has historically been a component of paediatric treatments for this lymphoma. At present, it is possible to cure this disease without using radiotherapy, the main cause of the most frequent long-term sequelae and complications. The evolution of treatment for paediatric Hodgkin lymphoma is discussed, highlighting the reported evidence of studies supporting a high survival rate without radiotherapy.