P1252 Prevalence, Incidence and Mortality of Pediatric Inflammatory Bowel Disease in Catalonia
E Brunet, I Loverdos, E Vela, C Comalrena de Sobregrau, D Garcia-Tirado, L Melcarne, C Pontes, L P Llovet, B Garcia-Sague, L E Frisancho, S Lario, A Puy, M J Ramirez-Lazaro, A Villoria, X CalvetAbstract
Background: Introduction
The epidemiologic status of pediatric inflammatory bowel disease (PIBD) has not been widely studied in Western Europe. The prevalence and incidence trends of the disease are largely unknown. The aim of this study is to determine the prevalence and incidence of PIBD and its mortality rate in Catalonia in the period 2011-2023.
Methods: Material and methods
A longitudinal study was performed using population-based data from the Catalan Health Surveillance System (CHSS). Data on prevalence, incidence and mortality of IBD in patients under the age of 18 years were obtained. Trends in age- and sex-adjusted rates were estimated. Crohn's disease (CD) and ulcerative colitis (UC) were also analysed separately.
Results
The number of PIBD patients rose from 307 in 2011 to 725 in 2023, with increases of 173% in UC and 113% in CD. The age- and sex-adjusted prevalence of PIBD rose from 23 (95%CI 20.5-25.7) to 48.1 (95%CI 44.7-51.7) per 1,000,000 inhabitants, while the annual incidence doubled, from 81 to 168. Although the peak incidence was recorded in 2022, the data suggest a flattening of the incidence curve in recent years. Seven patients died during follow-up, although the mortality rates were too low for further analysis.
Conclusion
Conclusion: The prevalence of PIBD is increasing rapidly in Catalonia. We observed also a trend towards a plateauing in the incidence that may suggest that prevalence might stabilize in the coming years.
References
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