P1217 Epidemiology and Temporal Trends of IBD in Central Taiwan

Background

Inflammatory Bowel Disease (IBD), as a chronic inflammatory disease of the gastrointestinal tract, encompasses Crohn's disease (CD) and ulcerative colitis (UC). With industrialization and advancements in healthcare, the prevalence of IBD in Taiwan is on the rise.

Methods

This study collected data from 593 IBD patients treated at Changhua Christian Hospital and China Medical University Hospital, analyzing the epidemiology of IBD in central Taiwan.

Results

The cohort included 200 CD and 393 UC patients, with an average age of 40.62 ± 15.08. CD exhibited a higher male proportion than UC (72.50% vs. 62.09%, p = .012). CD patients also had higher rates of appendectomy, bowel resection, and perianal disease surgery before IBD diagnosis, along with increased use of steroids, immunosuppressants, and biologics compared to UC. Over time, Taiwan's UC to CD ratio decreased (≦2005: 2.50; 2006-2015:2.06; 2016-2023:1.76), and CD's L2 location and B3 behavior proportions also declined. The proportion of the UC patients with location E1 was increased.

Conclusion

Taiwan's IBD population mimics patterns observed in high-income countries, with a declining UC to CD ratio. The reduced L2 location and B3 behavior in CD and suggest improved diagnostic awareness and more comprehensive colonoscopy examinations in Taiwan.

References

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