P-95: Risk of trauma-related hospitalization in young adults with type 1 diabetes: a nationwide historical cohort study
N Levran, A Vinograd, S Gendler, N Levek, I Radomislensky, A Afek, G Twig, O Pinhas-HamielAbstract
Introduction
Type 1 diabetes (TID) is a lifelong condition marked by glycemic instability and progressive microvascular complications that may increase physical injury risk. Hypoglycemia episode complications, such as neuropathy and retinopathy, can impair cognition, sensation, balance, and vision, potentially increasing vulnerability to trauma. Prior data suggest elevated trauma and hospitalization risk among adults with T1D; however, nationwide evidence in youth and young adults remains limited.
Objectives
To quantify the risk of trauma-related hospitalization and severe injury in young adults diagnosed with T1D during adolescence versus healthy controls.
Methods
This nationwide historical cohort study cross-referenced the Military Health Examinations Database (MHED) and the National Trauma Registry (INTR). The population included individuals assessed before military recruitment between 2008 and 2020 at ages 16.5–18 years. The exposure group comprised individuals with a T1D diagnosis code. Analysis was conducted across two cohorts: the total population and a “medically non-combat eligible” cohort to minimize bias from military service risks. Primary outcomes included hospitalization for injury and injury severity (ISS).
Results
In the total population analysis (n=868,982), 2,898 individuals had T1D. Trauma-related hospitalization was 1.28% (n=37) in the T1D group compared to 1.91% (n=16,561) in the non-diabetic population (p=0.013). Restricting analysis to the medically non-combat eligible cohort (n=255,461) showed no significant difference in injury rates between T1D and control (n=3,690, 1.46%; p=0.411). Gender stratified analyses confirmed no significant risk elevation for females (0.84%; p=0.483) or males (1.58%; p=0.384).
Conclusions
Individuals with T1D were not at increased risk of serious injury-related hospitalization. These findings suggest that adolescents and young adults with T1D may effectively mitigate trauma risk, potentially through heightened self-awareness, education, and preventive behaviors.