P-70: Minimal school-day glycemic interruptions in children using an advanced hybrid closed-loop (AHCL) system
J Cardin, M Liu, C Rodriguez, R Vigersky, J McVeanAbstract
Introduction
School-day glycemic events in children with type 1 diabetes have been reported to occur commonly, raising concerns about distracted learning. These events have also been reported to occur more frequently in those with a lower HbA1c.1 Whether AID systems mitigate school-day glycemic events, and how these events relate to overall glycemia, remains unclear.
Objectives
In this analysis, we analyzed school-day hyperglycemic events, hypoglycemic events and insulin delivery characteristics in almost 40,000 children using the MiniMedTM 780G (MM780G) system.
Methods
De-identified real-world ‘Carelink Personal’ data from 39,437 children ≤15 years using the MM780G system in the U.S. and EMEA region were analyzed from September 2024 to May 2025 (GMI <7: n=20,410; GMI ≥7: n=19,027). Participants with ≥10 days of data were stratified by GMI (<7% vs ≥7%). Events were defined as system mandated SG alerts delivered for sustained hyperglycemia (>250 mg/dL for 3 hours) or hypoglycemia (<54 mg/dL) and were calculated along with other glycemic and pump usage metrics during weekdays from 08:00-15:00.
Results
Weekly school-day glycemic event rates were low across both groups (GMI <7% vs ≥7%), (see table 1). Carb entries were 2.3 events/day versus 1.5 events/day, respectively. Auto bolus insulin comprised a large percentage of insulin delivered during the school day ranging from 22.9% to 40.9% of total bolus insulin delivered by the system.
Conclusions
In children using the MM780G system, school-day glycemic alarms were infrequent across both groups. Alarm patterns reflected underlying glycemia, with slightly more hypoglycemic alerts in those with GMI <7% and more hyperglycemic alerts in those with GMI ≥7%. This data suggests that AID systems support improved glycemic control without increasing (and potentially mitigating) school-day disruptions.