P-465: Diabetes ketoacidosis in young adult after transition to adult hospital

Introduction

The care of type 1 diabetes (T1D) is very huge obstructed during young adult when are transit to adult care centers or hospitals.

Objectives

The aim of study is to characterize the clinical and biochemical of young adult (16-35 years) who had admitted with diabetic ketoacidosis (DKA) at Cambodia Korea diabetes center of Cambodia-China friendship Kossamak hospital.

Methods

Retrospective study of patients who are admitted young adult type 1 diabetes in Cambodia-Korea diabetes center of tertiary-care Cambodia-China friendship Kossamak hospital. Opinion sampling of adolescents from 01 Jan 2024-31 Dec 2025 was collected.

Results

We included 13 patients among 34 type 1 diabetes admitted cases with age between 17-39 years old and mean age is 23 years. Duration of diagnosed was mostly >10 years and longest was 14 years. The most reasons of diabetes ketoacidosis were 7 cases (53.8%) co-infection, 2 (15.38%) missed follow up, 1 (7.69%) traffic accident, 3 (23.07%) unknown causes.

76.9% of patients were admitted at ICU with insulin infusion and 23.1% mild cases with subcutaneous insulin. The mean ICU stay of 3 days (+/- 1) before transferred to Cambodia-Korea diabetes center ward. Among of 13 cases, 1 (7.69%) stage-5 CKD. 27% were anemia (Hb:8.3-10g/dl), 96% were uncontrolled diabetes with HbA1c between >7-15.4%. Most of them were under premix insulin (67.3%) and basal-bolus insulin management (32.7%) after discharged.

Conclusions

Young adult living with type 1 diabetes are frequently meeting to many complications such as ketoacidosis, hypoglycemia and infections. Therefore, screening and prevention for conditions such as infections, complication and mental health disorders should be implemented. Self preparation, family and social supporting as well as peer educator should also be encouraged before and after transition to young adult type 1 diabetes.