DOI: 10.1093/bbb/zbag119 ISSN: 1347-6947
OpenMebius2: GUI-based software for 13C-metabolic flux analysis with tracer labeling pattern suggestions for precise flux predictions
Tatsumi Imada, Hiroshi Shimizu, Yoshihiro ToyaAbstract
13C-metabolic flux analysis (¹³C-MFA) is a crucial technique that experimentally determines metabolic flux distribution. Although precision of each flux strongly depends on tracer labeling pattern, its optimization remains challenging. We developed an integrated platform, OpenMebius2, a graphical user interface (GUI)-based software for ¹³C-MFA that includes a tracer labeling pattern suggestion function to support subsequent experiments.