DOI: 10.1039/d6ob01034b ISSN: 1477-0520

One-pot sugar conversion to N -aryl pyrrole-2-carbaldehydes for the synthesis and cytotoxic evaluation of lamellarin R analogues

Dabin Kim, Sangheon Ji, Ziyuan Luo, Hongyu Zhu, Shuangshuang Yin, Haiyang Yu, Sangho Koo

Ribose conversion provides an efficient route to lamellarin R analogues, enabling rapid SAR exploration. Key aryl substituents were identified for enhanced and selective cytotoxicity.

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