DOI: 10.1039/d6qo00583g ISSN: 2052-4129
One-pot access to quinoline–chalcone hybrids via the iron-catalyzed aerobic oxidative sp 3 C–H activation of unactivated alkylquinolines
Sangmyung Han, Seok Beom Lee, Jinwoo Lee, Hyungwoo Choi, Joonseok Jang, Suckchang HongOne-pot strategy for the direct synthesis of quinoline–chalcone hybrids from unactivated 4-alkylquinolines is developed via sequential iron-catalyzed aerobic oxidative sp 3 C–H activation and aldol condensation.