Of Silicon and Cells: Ethical and Safety Concerns Regarding Artificial Intelligence Usage in the Biomedical Sciences—A Narrative Review

Artificial intelligence (AI), most pointedly through advancements in large language models (LLMs), has dominated the media and has expansive promise in improving productivity in a myriad of fields, notably the life sciences. The expansion of AI into the field has encompassed nearly every domain from research to healthcare and appears to have an inertia that will make it difficult to change the course of its adoption. Given this rapid pace of adoption, it is crucial to reflect on these advancements and their place in the modern life sciences to understand the evolving ethical, medico-legal, and scientific challenges the use of such technology poses for practitioners of the life sciences, specifically, the biomedical sciences. Herein, the authors narratively review the current usage of AI with respect to clinical care, research production and integrity, as well as an epidemiologic purview of technology.