DOI: 10.1039/d6gc03246j ISSN: 1463-9262

Nucleophilicity-controlled stereodivergent synthesis of ADP-ribosylated phenols and tyrosine derivatives directly from β-NAD +

Yanbo You, Munong Li, Nan Lv, Ruotong Zhai, Yiran Liu, Dongshuang Fan, Ruifeng Zhang, Anlian Zhu, Lingjun Li

A nucleophilicity-controlled stereodivergent strategy was developed for converting readily available β-NAD + into α- or β-configured ADP-ribosylated phenols and tyrosine derivatives.