DOI: 10.1039/d6np00070c ISSN: 0265-0568
NRPS megasynthases – the A to X of assembling peptide antibiotics
Xinyun Jian, Mathias H. Hansen, Lauren A. M. Murray, Max J. CryleNRPS megasynthases are diverse assembly lines that produce many important antibiotics. Here, we summarise recent discoveries in the NRPS antibiotics field, revealing the incredible diversity of these machineries and the molecules they biosynthesise.