Not Your Typical Vaginal Bleed: Inflammatory Bowel Disease in a Sigmoid Neovagina

ABSTRACT

A 31-year-old woman with mullerian agenesis and a neovagina derived from the sigmoid colon presented with bleeding per vaginum along with luminal gastrointestinal symptoms. Diagnostic evaluation revealed ulcerative colitis (UC) involving the native colon and neo vagina. Both her gastrointestinal and vaginal symptoms responded very well to conventional UC treatment. This case highlights a rare complication of UC in patients with Mullerian agenesis who have undergone sigmoid colon vaginoplasty. The association between UC and neovaginal bleeding underscores the need for careful monitoring and early intervention in such complex cases to prevent further morbidity and improve patient outcomes.