DOI: 10.1055/a-2897-5924 ISSN: 0936-5214
Non-directed Pd/S,O-ligand-catalyzed C-H arylation of anisole derivatives under mechanochemical conditions
Alen Bjelopetrović, M. Angeles Fernandez-IbañezNon-directed Pd/S,O-ligand-catalyzed C–H arylation of anisole derivatives under mechanochemical conditions is described. This ball-milling protocol employs the arene as the limiting reagent, significantly reduces the amount of HFIP needed, and operates under mild conditions, providing a greener approach to biaryl synthesis.