DOI: 10.1039/d6cc02855a ISSN: 1359-7345
Non-covalent aptamer decoration promotes THP1-MØ phagocytosis of bacteria by enhancing target proximity
Shizuka Kuchiki, Maasa Yokomori, Susumu Muto, Yuki Inami, Hiroharu Yui, Keitaro YoshimotoWe report a noncovalent strategy to install cholesterol-conjugated DNA aptamers on THP1-MØ membranes by lipid insertion, thereby increasing target–effector proximity and promoting bacterial phagocytosis.